Data for peptidomic analysis of a single mouse hypothalamus

Yusei Okuda; Yuzuru Nakagawa; Takashi Matsui; Ryo Konno; Yusuke Kawashima; Toshiya Sato; Makoto Itakura; Yoshio Kodera

doi:10.14889/jpdm.2024.0015

Yusei Okuda, Yuzuru Nakagawa, Takashi Matsui , Ryo Konno, Yusuke Kawashima, Toshiya Sato, Makoto Itakura, Yoshio Kodera

Author information

Yusei Okuda
https://orcid.org/0009-0000-5473-9503
Department of Physics, School of Science, Kitasato University, Japan
Yuzuru Nakagawa
Department of Physics, School of Science, Kitasato University, Japan
Takashi Matsui Corresponding author
https://orcid.org/0000-0002-4496-2389
Department of Physics, School of Science, Kitasato University, Japan
Center for Disease Proteomics, School of Science, Kitasato University, Japan
Ryo Konno
https://orcid.org/0000-0002-4375-1133
Department of Physics, School of Science, Kitasato University, Japan
Yusuke Kawashima
https://orcid.org/0000-0002-9779-8199
Department of Applied Genomics, Kazusa DNA Research Institute, Japan
Toshiya Sato
https://orcid.org/0000-0001-7844-9930
School of Medicine, Kitasato University, Japan
Makoto Itakura
Center for Disease Proteomics, School of Science, Kitasato University, Japan
School of Medicine, Kitasato University, Japan
Yoshio Kodera Corresponding author
https://orcid.org/0000-0002-6661-8677
Department of Physics, School of Science, Kitasato University, Japan
Center for Disease Proteomics, School of Science, Kitasato University, Japan

Keywords: peptidomics, Bioactive peptide, mass spectrometry, Mus musculus, Hypothalamus

JOURNAL OPEN ACCESS
Supplementary material

2024 Volume 6 Pages 15-

DOI https://doi.org/10.14889/jpdm.2024.0015

Details

Abstract

In this study, the differential solubilization method was modified to extract peptides from small amounts of frozen tissue. As a result, we successfully identified a total of 1,535 peptides including 35 bioactive peptides from 135 μg of mouse hypothalamus in three measurements.

Corresponding author

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