2024 Volume 6 Pages 16-
Serum proteins enriched with 35 different lectins were analyzed by LC-MS/MS. The results showed that enrichment with Solanum tuberosum lectin (STL) and Lycopersicon esculentum lectin (LEL) resulted in the detection of many trace proteins in the serum. The combination of lectins was also examined, and the combination of STL and LEL was found to be the best for observing serum trace proteins. We aplied the STL/LEL method to sera from systemic lupus erythematosus (SLE) model mice and control mice, and compared them.