Data for Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens

Yuichi Abe; Hidekazu Hirano; Hirokazu Shoji; Narikazu Boku; Takeshi Tomonaga; Jun Adachi

doi:10.14889/jpdm.2024.0024

Yuichi Abe, Hidekazu Hirano, Hirokazu Shoji, Narikazu Boku, Takeshi Tomonaga, Jun Adachi

Author information

Yuichi Abe
https://orcid.org/0009-0004-3092-4201
Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
Hidekazu Hirano
Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
Hirokazu Shoji
Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
Narikazu Boku
Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
Takeshi Tomonaga
Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
Proteobiologics Co., Ltd., Osaka, Japan
Jun Adachi Corresponding author
Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan

Keywords: phosphoproteomics, kinome, gastric cancer, endoscopic biopsy

JOURNAL OPEN ACCESS
Supplementary material

2024 Volume 6 Pages 24-

DOI https://doi.org/10.14889/jpdm.2024.0024

Details

Abstract

Cancer phosphoproteomics provides insights into actionable kinases for targeted therapies. Monitoring phosphoproteomics in cancer is crucial for optimizing treatments with kinase inhibitors. We have developed a highly sensitive method for analyzing phosphoproteomics in endoscopic biopsies. Our approach aims to enhance the accuracy of monitoring therapeutic kinase activities.

Corresponding author

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