Dataset for proteomic analysis of 31 patient-derived sarcoma cell lines and their original tumor tissues

Abstract

To explore both differences and similarities in proteomic characteristics between patient-derived sarcoma cell lines and their corresponding tumor tissues, we performed 62 LC-MS/MS analyses on 31 sarcoma patient-derived cell lines (PDCs) and their tumor samples. The number of peptides and proteins identified was highly comparable between the two datasets. These comprehensive proteomic profiles also identified druggable cancer-related proteins, offering potential insights into therapeutic targeting.