Proteomic analysis data of 35 patient-derived sarcoma cell lines and their original tumor tissues

Abstract

To investigate the proteomic similarities and differences between patient-derived sarcoma cell lines (PDCs) and their corresponding tumor tissues, we performed 70 LC-MS/MS analyses on 35 matched sample pairs. The number of identified peptides and proteins were highly comparable between the two groups. These comprehensive proteomic profiles enabled the identification of druggable cancer-related proteins, providing potential insights into therapeutic targeting.