Development of the novel fungicide fenpyrazamine

Abstract

Fenpyrazamine is a novel fungicide with an aminopyrazolinone structure developed by Sumitomo Chemical Co., Ltd. Fenpyrazamine has good fungicidal properties, such as high antifungal activity, preventive activity, translaminar activity, inhibition activity in lesion development, and long lasting activity. The target enzyme of fenpyrazamine is 3-keto reductase in the ergosterol biosynthetic pathway. Fenpyrazamine shows high efficacy against gray mold, stem rot, and brown rot in field trials. Formulated products, PROLECTUS^® and PIXIO^®DF, have been registered since 2012. PROLECTUS^® was first launched in Italy in 2012, and PIXIO^®DF was launched in Japan in 2014.