Journal of Pesticide Science
Online ISSN : 1349-0923
Print ISSN : 1348-589X
ISSN-L : 0385-1559
In vitro investigation of anticholinesterase activity of four biochemical pesticides: spinosad, pyrethrum, neem bark extract and veratrine
Madalina Petruta BucurBogdan BucurJean-Louis MartyGabriel-Lucian Radu
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JOURNALS FREE ACCESS Advance online publication

Article ID: D13-062

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Abstract

The anticholinesterase activity of four biochemical pesticides: spinosad, pyrethrum, neem bark extract and veratrine was tested against one acetylcholinesterase extracted from Electrophorus electricus and two from Drosophila melanogaster. Pyrethrum, neem bark extract, and veratrine induced a dose-related inhibition of a variable type. Electric eel cholinesterase was inhibited uncompetitively by neem bark extract, the inhibition of the wilde-type fruit fly enzyme by pyrethrum was competitive, and the other enzyme-biochemical pesticide inhibitions were non-competitive. The sensitivity of each enzyme toward biochemical pesticides was variable.

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© 2014 Pesticide Science Society of Japan
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