Abstract
Condensation of amidinohydrazones with ethoxymethylenemalononitrile gave 2, 3-dihydro[1, 2, 4]triazolo[1, 5-c]pyrimidines in moderate to high yields. Of the variously substituted amidinohydrazones, aldehyde 4-monosubstituted ones were most reactive in the condensation, regardless of the nature of the 4-substituent. The 2, 3-dihydro compounds were oxidized with iron (III) chloride in aqueous acetic acid or with iodine in ethyl alcohol to give the corresponding [1, 2, 4]triazolo[1, 5-c]pyrimidines. Thirty-eight compounds were subjected to fungicidal screening tests, which showed no or weak activity against test organisms.
