Abstract
Two fungicidal substances, Y-9 and Y-10, were isolated from the culture filtrate of Bacillus subtilis TM-105 during our screening for antimicrobial substances against phytopathogenic fungi. They were identified as lipopeptide antibiotics plipastatin A1 and B1, respectively. Plipastatins have been reported to be new inhibitors of phospholipase A2, but their fungicidal activity has yet to be clarified. We report here the result of our investigation on the fungicidal activity of plipastatins.