Summaries of Toxicity Studies on Quinclorac

Abstract

In order to investigate toxicological properties of Quinclorac, a number of toxicological studies were carried out with QUINCLORAC TECH and FACET WP. From these studies, it can be derived that the acute toxicity, subacute toxicity, and long-term toxicity are rather low. No critical irritant effects on eye and skin were noted, and under practical conditions a skin sensitizing effect and inhalation risk can be excluded. No adverse effect was observed on reproductivity, and no signs of teratogenic effects were noted. Mutagenicity was negative at non cytotoxic levels. There were no signs of an oncogenic response in any of the tested animals.
A withholding value has been set for the registration at 0.5ppm on rice, and FACET WP, wettable powder formulation containing 50% Quinclorac, was registered to JMAFF on November 16, 1989.
A safety risk for Quinclorac, as far as it is used in accordance with the established safe use standard, is not to be expected.