Abstract
A lot of toxicology studies were carried out in order to investigate toxicological properties of technical pyrimidifen and it's formulation (4%-SC). The results of acute toxicity tests indicate that pyrimidifen technical displays moderate toxicity and it's formulation display much lower toxicity than pyrimidifen technical. Pyrimidifen should be handled carefully because of eye irritation and inhalation toxicity. In chronic toxicity studies, some effects as depression of body weight gain, lower food consumption and small changes in organs were generally observed at higher dose levels. In dogs, clinical signs of liquid faeces and vomiting were also observed at higher dose. In any test and any animal, the NOELs were confirmed.
Pyrimidifen is not genotoxic or oncogenic and does not interfere with normal reproduction and development.
When the rules for usage of pyrimidifen are kept, it is not only an effective acaricide and insecticide but a safe one.
Pyrimidifen is considered to be one of the most useful agricultural materials.
