Synthesis of Some 4-Thiazolines from Unsymmetrical Thioureas and their Fungicidal Activity

Abstract

Fortyone new 4-thiazolines have been synthesised by the condensation of unsymmetrical diarylthioureas of the type RNHCSNHR' with ketones in presence of bromine as the condensing agent. In majority of these condensations only one isomer has been isolated. All the prepared thiazolines have been tested for their ungicidal activity against Cochliobolus miyabeanus as the test fungus and the I₅₀ in ppm (50% inhibition) value have been reported in Table 1.