Abstract
Some antilipidemic agents of several different chemical classes and their related compounds were synthesized, and their ovicidal activities were assayed on freshly laid eggs of the azuki bean weevil, Callosobruchus chinensis. In general, those chemicals which have been reported to possess antilipidemic activity showed moderate ovicidal activity. The antilipidemic agent clofibrate [ethyl α-(4-chlorophenoxy)-α-methylpropionate], which has been reported to have acute toxicity on the milkweed bug, showed considerably high ovicidal activity. However, none of the α-(4-chlorophenoxy)-α-methylpropionic acid amides had ovicidal activity. Ethyl 2, 2, 3-trimethyl-4-(4′-chlorophenyl)-3-butenoate showed the highest ovicidal activity among the tested compounds.
