The Journal of Physical Fitness and Sports Medicine
Online ISSN : 2186-8123
Print ISSN : 2186-8131
ISSN-L : 2186-8131
Short Review Article
The effects of exercise on adipokines -Focus on circulating adiponectin level in human studies-
Shigeharu Numao
ジャーナル フリー

2012 年 1 巻 3 号 p. 531-535


Adipose tissue is an important site for energy storage and energy homeostasis. In addition, it has been recognized as an endocrine organ that produces and secretes a number of bioactive peptides or proteins called “adipokines”. These molecules are directly and indirectly involved in the pathogenesis of metabolic disorders, such as obesity, type 2 diabetes, cardiovascular diseases, and metabolic syndrome. Until now, a number of adipokines (e.g. adiponectin, leptin, tumor necrosis factor-α interleukin-6, and retinol-binding protein-4) have been identified and their functions have been elucidated. Among these, adiponectin is known to be involved in improvement in insulin sensitivity and endothelial function, and promotion of fat oxidation. Aerobic exercise also has the same effects. The benefits of aerobic exercise could be induced through changes in adiponectin levels. In this short-review, focus is given to the effects of aerobic exercise on circulating adiponectin levels in humans.

© 2012 The Japanese Society of Physical Fitness and Sports Medicine
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