The Journal of Physical Fitness and Sports Medicine
Online ISSN : 2186-8123
Print ISSN : 2186-8131
Short Review Article
Effects of exercise on glucagon-like peptide-1 (GLP-1)
Shin-ya UedaHidehiro NakaharaTadayoshi Miyamoto
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Volume 2 (2013) Issue 2 Pages 221-224

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Appetite and eating behaviour are controlled by a variety of peripheral signals that change in response to food intake and act in the hypothalamus and brainstem. Glucagon-like peptide-1 (GLP-1) is a brain-gut peptide that has a variety of physiological functions and is involved in appetite regulation. Abnormalities in the expression and secretion of GLP-1 have been shown to occur in obesity, diabetes, and hyperlipidemia, and improving these abnormalities has become an important challenge. Exercise has recently been shown to have an influence on GLP-1 concentrations. This short review aims to highlight the association between exercise and the blood kinetics of GLP-1 and discuss the relevance of GLP-1 in the regulation of appetite to prevent obesity.

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© 2013 The Japanese Society of Physical Fitness and Sports Medicine
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