The Journal of Physical Fitness and Sports Medicine
Online ISSN : 2186-8123
Print ISSN : 2186-8131
ISSN-L : 2186-8131
Review Article
Benefits of post-stress immunosuppression: a viewpoint from exercise immunology
Hiromi YanoMichael J. KremenikMasataka UchidaEri Oyanagi
キーワード: open window theory, TLR, TNF-α
ジャーナル フリー

2018 年 7 巻 3 号 p. 153-159


In understanding the relationship between exercise and immunity, the “open window theory” is a well-known theory stating that immediately after high intensity exercise, temporary immunosuppression occurs, which increases the risk of infections such as upper respiratory tract infections. Why does such a phenomenon occur? Does immunosuppression after severe exercise have physiological significance? In this paper, we propose a theory of super homeostasis. In other words, we verify that the open window theory is an important biological reaction when trying to understand the reason why we do exercise, more than it is the indispensable physiological response to the whole body.

© 2018 The Japanese Society of Physical Fitness and Sports Medicine