抄録
The salivary glands, which are innervated by both sympathetic and parasympathetic nervous systems, receive their main secretory innervation from the parasympathetic nervous system (1). It was reported that sympathetic nervous system played an important role in secretion of amylase, a main component of parotid saliva, and that the β receptors were the ones involved in this mechanism (2-5). It was also reported that nicotine caused an increase in amylase secretion as well as salivary flow and suggested that the increasing effect of nicotine on amylase secretion was not due to the direct action on the ganglion, but the action of catecholamine released from adrenal medulla. The acceleration of nicotine in salivary flow, however, was not explained in the same way (6, 7). On the other hand, it was proposed in various organs that symapthetic effect of tyramine was caused by a release of noradrenaline from sympathetic nerve endings (8). It is, therefore, of interest to examine actions of tyramine on amylase secretion in comparison with those of nicotine.
