The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
EFFECT OF CHOLINERGIC DRUGS AND BARIUM ON OXYGEN CONSUMPTION IN GUINEA PIG TAENIA COLI
Yukio SAITOYutaka SAKAINorimoto URAKAWA
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1972 Volume 22 Issue 5 Pages 653-661

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Abstract
It has been reported that taenia coli isolated from guinea pig showed tension development accompanied by an increase in oxygen consumption when treated with a stimulant such as acetylcholine, eserine (1), histamine (1, 2) or high concentration of potassium in medium (3). An increase in oxygen consumption during histamine or high-K induced contracture is probably linked to increased Ca ions in the cytoplasm of the muscle cell (2, 4).
The present experiments were undertaken to investigate effects of carbachol, pilocarpine, atropine and barium on oxygen consumption, muscle tension and electrical activity in taenia coli.
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