STUDIES ON THE PHYSICAL DEPENDENCE LIABILITY OF ANALGESICS 3RD REPORT : ELECTRON MICROSCOPIC STUDY ON INTRAMITOCHONDRIAL STRUCTURE OF ZONA FASCICULATA CELLS IN ADRENAL CORTEX IN A NEW ANALGESIC, CG-315 CHRONICALLY ADMINISTERED RATS

Ichiro YANO; Hitoo NISHINO; Yasusuke MASUDA; Hiroyuki YAMAMOTO; Tadashi MURANO

doi:10.1254/jjp.23.227

STUDIES ON THE PHYSICAL DEPENDENCE LIABILITY OF ANALGESICS

3RD REPORT : ELECTRON MICROSCOPIC STUDY ON INTRAMITOCHONDRIAL STRUCTURE OF ZONA FASCICULATA CELLS IN ADRENAL CORTEX IN A NEW ANALGESIC, CG-315 CHRONICALLY ADMINISTERED RATS

Ichiro YANO, Hitoo NISHINO, Yasusuke MASUDA, Hiroyuki YAMAMOTO, Tadashi MURANO

Author information

JOURNAL FREE ACCESS

1973 Volume 23 Issue 2 Pages 227-231

DOI https://doi.org/10.1254/jjp.23.227

Details

Abstract

CG-315, an analgesic which formed no physical dependence in our experiments was incapable of inducing the transformation of intramitochondrial structure in adrenocortical cells after abrupt withdrawal of the drug in chronically administered rats in contrast to that in morphine addicted rats.

Corresponding author

Register with J-STAGE for free!