The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
STUDIES ON GASTROINTESTINAL HORMONES X. EFFECTS OF TETRAGASTRIN ON GASTRIC SECRETION AND ISOLATED SMOOTH MUSCLES
Kuniomi TACHIBANAHisatoshi KABENOYasuaki KOBAYASHI
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1973 Volume 23 Issue 2 Pages 233-242

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Abstract
Effects of TG on intestinal smooth muscle were examined using isolated guinea-pig ileum and for the effects on gastric secretion Schild's rats were used. Stimulant actions of TG on guinea-pig ileum may be indirect, that is, the stimulation of postganglionic parasympathetic nerves, leading to the release of acetylcholine. Gastric secretion stimulating action of TG on Schild's rats may be direct action to the oxyntic glands and it may be not mediated by released acetylcholine or histamine.
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© The Japanese PharmacologicalSociety
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