The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
ROLE OF CATECHOLAMINES IN THE MEDIATION OF PERIPHERAL EFFECTS OF FEMALE SEX HORMONES
J.P. BARTHWALT.K. GUPTAM.L. GUPTAK.P. BHARGAVA
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JOURNAL FREE ACCESS

1973 Volume 23 Issue 3 Pages 349-354

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Abstract
The effect of diethylstilboestrol (DES; 0.5 mg/100 g) and progesterone (2.5 mg/100 g) was studied on the catecholamine content of adrenals and uteri of seven day ovariectomized albino rats. The agents were administered i.p. on alternate days for one week and the tissue catecholamine content was determined spectrophotofluorometrically. DES treatment increased the total adrenaline contents of adrenals and uterus. On the other hand progesterone caused a decrease in the level of catecholamines in both the tissues. These findings are discussed in relation to the actions of female sex hormones on cardiovascular and genital systems.
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