Reversed Effects between Crude and Processed Ginger Extracts on PGF2α-Induced Contraction in Mouse Mesenteric Veins

Leonora Rivera PANCHO; Ikuko KIMURA; Ryoichi UNNO; Masayasu KURONO; Masayasu KIMURA

doi:10.1254/jjp.50.243

Reversed Effects between Crude and Processed Ginger Extracts on PGF_2α-Induced Contraction in Mouse Mesenteric Veins

Leonora Rivera PANCHO, Ikuko KIMURA, Ryoichi UNNO, Masayasu KURONO, Masayasu KIMURA

Author information

JOURNAL FREE ACCESS

1989 Volume 50 Issue 2 Pages 243-246

DOI https://doi.org/10.1254/jjp.50.243

Details

Abstract

The effects of crude and processed ginger extracts and pungent components, S-(+)-[6]-gingerol and [6]-shogaol, on noradrenaline (NA) and prostaglandin (PG) F_2α-induced contraction were investigated using mouse mesenteric veins. Both spicy constituents inhibited the contractile responses to NA. Crude ginger extract and S-(+)-[6]-gingerol potentiated the PGF_2α-induced contraction, whereas processed ginger extract and [6]-shogaol inhibited the contraction.

Corresponding author

Register with J-STAGE for free!