A case of cadmium nephropathy

Abstract

Described herein is a 31 year old Japanese male, who had been engaged in the operation of smelting alloys of silver and cadmium for about 10 years, with proteinuria and glucosuria, associated with a large quantity of cadmium excaetion into urine. Renal function tests revealed decreased GFR, RPF and PSP excretion. Histologically glomeruli were slightly enlarged and mesangium were hypertrophied, but no remarkable tubular abnormalities were noticed.