数式による透析効果の予知

抄録

If, by means of few simple formulae, we can determined the period and conditions of dialysis necessary for reducing the creatine (or BUN) concentration to arbitrary degree, it would be helpful for bettering dialystic treatment. Many factors have direct or indirect influences on dialystic results. Kinds of a dialyzer and dialy-sate flow rate being constant, the most influential factors on the required dialysis time are the quantity of body fluid and blood flow rate of patients. If we choose the time unit shown by follow, it was found experimentaly that is a definite regula-rity between the half life of decreasing creatinine (or BUN) concnetration degree and the blood flow rate. Dialysis Time Unit (D)=circulating blood volume (ml)/blood flow rate (ml/min)The unit per time period "D" is expressed by the minute unit of the time required for consumately passing through the dialyzer of same quantity of the circulating blood volume. If the conditions of dialyzer and blood flow rate are constant, about of all cases, the decreasing rate of creatinine (or BUN) concentration degree is constant in the time period " D ". With the period " D ", I have devised several formulae and graph of the formulae, the time required for necessary dialysis easelys determined.