抄録
Eleven specimens of renal biopsy from 5 patients with anaphylactoid purpura nephritis (group I ) and 4 selected patients with persistent microhematuria and/or proteinuria (group II) were examined in view of the pathological correlations between two groups. 1) By light microscopy, the lesions of group I cases ranged from "minimal change" to focal or diffuse mesangial proliferation, occasionally superimposed by crescents, whereas all cases of group 11 showed "minimal change" only. 2) On immunofluorescence, a predominant presence of granular deposits of both IgA and fibrinogen on the basement membrane was particularly characteristic and constant in all cases of both groups that might with ease differentiated in their location and appearance of the deposits from that of mesa-ngial "IgA nephropathy" cases. 3) Electron microscopy disclosed electron dense deposits on subendotherial side with some extention into a mesangial portion in all cases of both groups. Furthermore, subepitherial deposits were seen in two cases of group I. These findings would correspond in their location to the above immunofluorescent findings. From above findings it is suggested that the glomerulopathy of both groups appeared to be induced by a common pathogenetic mechanism and that the sizes of immune complex from both groups' cases might be smaller than that of "IgA nephropathy" and their small size could allow them to cross the glomerular basement membrane.
