日本腎臓学会誌
Online ISSN : 1884-0728
Print ISSN : 0385-2385
ISSN-L : 0385-2385
MPO-ANCA陽性で膜性腎症を示した高齢発症ネフローゼ症候群の1例
関根 淑江湯村 和子田中 裕子菅沼 信也大貫 隆子内田 啓子川嶋 朗本田 一穂新田 孝作二瓶 宏
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2002 年 44 巻 1 号 p. 44-49

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We report a rare case of nephrotic syndrome in an elderly woman with positive antineutrophil cytoplasmic antibody (ANCA) . The patient was 81 years of age and had a history of interstitial pneumonia. She was diagnosed rheumatoid arthritis (RA) at admission. Rapidly progressing renal damage was found with mild microscopic hematuria and positive ANCA. The renal biopsy findings indicated membranous nephropathy. Neither gold nor anti rheumatic drugs had been previously administered. She may have had an RAspecific membranous nephropathy. Crescentic formation was not clear. With hematuria, the leukocyte infiltration in the capillary lumen and the change in epithelial cells of Bowman's capsules would be histological findings suggesting ANCA-associated nephritis. This is a rare report on membranous nephropathy in an RA patient with ANCA associated nephritis.
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