A STUDY OF RENAL CLEARANCE TEST IN THE UROLOGICAL SURGERY (II. REPORT)
THE RENAL CLEARANCE TEST IN THE URETERO-ENTEROSTOMY
1954 Volume 45 Issue 9 Pages 553-560
Details
1954 Volume 45 Issue 9 Pages 553-560
The renal plasma flow (RPF) (with sodium para-amino hippurate), the renal blood flow (RBF), the glomeruar filtration rate (GFR) (with sodium thiosulfate) and the filtration fraction (FF) were measured on 7 dogs in which the both ureters were transplanted into the isolated portion of the sigmoid with the combination of Coffey I method and Kerr-Colby method to have an artificial sigmoid bladder.
The results were as follows:
1. Preoperatively, RPF was 177-331cc/min, on the average 226cc/min, RBF was 300-551.7cc/min, on the average 383cc/min, GFR was 57-88.8cc/min, on the average 71.8cc/min and FF was 0.27-0.38, on the average 0.32.
2. Postoperative changes.
a. Of the 7 dogs, 2 dogs were survived, 3 dogs died on the 14th. -23rd, postoperative day due to ascending infection of the upper urinary tracts or due to stenosis of the anastomosis site and 2 dogs died on the 4th. -7th. postoperative day due to the operation.
b. For 24 hours after the operation marked damages of the renal function were seen. RPF, RBF and GFR decreased to 31.5-47.4, %, 23.4-4% and 41-50% of each preoperative rate.
c. In all dogs except 2 dogs which died due to the operation RPF, RBF and GFR were restored to 60%, 60-70% and 67.3-86.9% of each preoperative rate. On the other hand, 2 dogs which died due to the operation did not show any evidence of restoration.
d. In 2 dogs which were survived for long time all three values were restored gradually to the preoperative rate within 3 weeks after the operation. GFR was restored more slowly than RPF and RBF. However, in 3 dogs which died on the 14th. -23rd. day, RPF, RBF and GFR began to decrease again from the 2nd, week after the operation.
