A STUDY OF IRRIGATING FLUID IN A TREATMENT OF ANURIA

Abstract

Peritoneal irrigation for positive renal compensation of a temporaly renal insufficiency way first devised by Ganter and have were attempted by many investigators. Oder and others have reviewed electrolytic composition of irrigating fluids for peritoneal lavage from 101 clinical cases.
Recent man had regard to electrolyte balance at the peritoneal irrigation. It is ideal that electrolyte pathern of irrigating fluid change in proportion as a state of electrolyte unbalance at anuria. But it is difficult that man make a fit solution for a burning clinical case.
I maked experiment to prepare a better solution for anuria. Rabbit, which cocured nephrectomized anuria and anuria of mercuric poisoning, have were irrigated two solutions; one include potassium and another not it. The results obtained were as follows.
1) There is no difference of Na⁺, Cl^-, HCO_3--pathern in serum bitween use of two solutions. HCO₃-pathern in serum approached to normal and latent acidosis was compensated.
2) Hyperpotassemia drew down to normal, however the solution, that it not included potas sium, had better ability of dialysis than another.
3) Excretion of toxic product; Non-Protein-Nitrogen are equal.
4) Ascent of bloodsugar and excreation of Glucose in urine were recognized.
5) Peritoneal irrigations employed 3 clinical cases and 2 patients recovered. One case was anuria which appeared to be due to food intoxication and another was acute glomerulonephritic oliguria. Last case of uraemia by chronic nephritis died.