STUDIES ON THE EFFECTS OF ACTH, CORTISONE AND ADRENALIN ON ASCORBIC ACID IN RABBITS ORGANS

Abstract

Ascorbic acid in the pituitary body, adrenal gland, spleen, liver, kidney, testis, prostatic gland and in blood was determined by the administration of ACTH, cortisone, adrenalin and the effects of these hormones were investigated.
Ascorbic acid in blood diminished remarkably by adrenalin, indefinite by cortisone and not always increased by ACTH.
Ascorbic acid in adrenal gland showed remarkable decrease by ACTH and slightly decrease by adrenalin.
Ascorbic acid in spleen showed slightly decrease by ACTH and, contrarily, moderate increase in liver.
In testis, special changes could not be found and also, no significant changes could be found in prostatic gland. The physiological response of ascorbic acid on male sexual accessary organs could not be solved.