HEMOSPERMIA

Abstract

Hemospermia is defined as a bloody codition of the sperm. As its etiology is unknown, the treatment for it has not been established.
It is believed that the site of bleeding lies in the route of genito-urinary system. There are only a few cases of organic hemospermia, the majority of the cases being essential hemospermia.
Clinical and statistical observations were carried out on 30 cases of hemospermia. Spermatocystectomy was performed on some of them, and the samples of seminal vesicles were investigated histologically. The following catarrhal changes were noted:
1. Atrophy and exfoliation of the epidermal cells.
2. The stasis of the submucosal capillary vessels.
3. Infiltration by the round cells inclunding the plasma cells.
These changes were thought to be manifestations of allergic reactions. In order to grove this point, though experiments were carried out. By using the serum of pig, the antigen-antibody reaction was caused to occur in the seminal vesicles of mature rabbits. The observations made were similar to those observed in clinical hemospermia.
Seminal vesicle absorption tests were carried out with Santozol in patients with hemospermia and other diseases of the seminal vesicles. The absorption curve obtained in the former was different from the latter. This seems to indicate that the seminal vesicle absorption test using Santozol is of value as a tool of differential diagnosis of essential and organic hemospermia.
In some patients with this disease, anti-allergic agent provided marked improvement. This seems to support the author's view, based on clinical expriences and animal experiments, that some of the cases of hemospermia are allergic in origin.