The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
Volume 54, Issue 2
Displaying 1-6 of 6 articles from this issue
  • WITH SPECIAL REFERENCE TO THE EFFECT OF ANDROGENIC HORMONE
    Munenori Shibuya
    1963 Volume 54 Issue 2 Pages 111-135
    Published: 1963
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The fine structure of the epithelial cells of the ventral lobe of rat prostate has been investigated by means of electron microscope. Normal structure of the cells is as follows: the tall cuboidal epithelium contains well-developed rough surfaced endoplasmic reticulum, which presents a concentric lamellar arrangement on transverse section, running parallel to the long axis on longitudinal section. Golgi complex mainly consists of vacuoles and vesicles, occasionally intermingling multivesicular bodies. Mitochondria are oval or rod-shaped as seen in cells of other organs. The cell membrane exhibits a “unit membrane structure”. And there are some cells which show “anastomotic intercellular bridge” between each other.
    The effect of androgen on the prostatic epithelium has been investigated on adult rats. They were divided into four groups. The rats of Group 1 were injected daily 0.5mg of testosterone propionate intramuscularly for succesive ten days. The daily doses of testosterone propionate for the same periods in Group 2, 3 and 4 were 1.0mg, 2.0mg and 4.0mg, respectively. The higher doses were given, the more marked changes of the cellular organellae are observed. The findings in Group 1 are nearly alike to those of the normal rats, while in Group 2, 3 and 4 the changes of endoplasmic reticulum are evident: distorsion of parallel lamellar arrangement and dilatation of cisternae. Representative changes in Golgi complex are widening of Golgi zone and increase of multivesicular bodies. Mitochondria become also enlarged and arrangement of them presents a close topographical relationship with endoplasmic reticulum.
    These findings indicates that administration of testosterone propionate resulted in enhancement of cellular activity of the rat prostatic epithelium
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  • Hiroshi Endo
    1963 Volume 54 Issue 2 Pages 136-163
    Published: 1963
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Hemospermia is defined as a bloody codition of the sperm. As its etiology is unknown, the treatment for it has not been established.
    It is believed that the site of bleeding lies in the route of genito-urinary system. There are only a few cases of organic hemospermia, the majority of the cases being essential hemospermia.
    Clinical and statistical observations were carried out on 30 cases of hemospermia. Spermatocystectomy was performed on some of them, and the samples of seminal vesicles were investigated histologically. The following catarrhal changes were noted:
    1. Atrophy and exfoliation of the epidermal cells.
    2. The stasis of the submucosal capillary vessels.
    3. Infiltration by the round cells inclunding the plasma cells.
    These changes were thought to be manifestations of allergic reactions. In order to grove this point, though experiments were carried out. By using the serum of pig, the antigen-antibody reaction was caused to occur in the seminal vesicles of mature rabbits. The observations made were similar to those observed in clinical hemospermia.
    Seminal vesicle absorption tests were carried out with Santozol in patients with hemospermia and other diseases of the seminal vesicles. The absorption curve obtained in the former was different from the latter. This seems to indicate that the seminal vesicle absorption test using Santozol is of value as a tool of differential diagnosis of essential and organic hemospermia.
    In some patients with this disease, anti-allergic agent provided marked improvement. This seems to support the author's view, based on clinical expriences and animal experiments, that some of the cases of hemospermia are allergic in origin.
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  • III EFFECT OF SMALL AMOUNT ANTIBIOTIC TREATMENT
    Masaru Kondo, Masao Naito, Nobuo Miki
    1963 Volume 54 Issue 2 Pages 164-167
    Published: 1963
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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  • Kinjiro Hirose
    1963 Volume 54 Issue 2 Pages 168-193
    Published: 1963
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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  • Tokuji Ichikawa, Masayoshi Waku, Akimi Ogawa, Koji Nakauchi
    1963 Volume 54 Issue 2 Pages 194-210
    Published: 1963
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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  • Yasuyuki Yonese
    1963 Volume 54 Issue 2 Pages 211-238
    Published: 1963
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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