ENDOCRINOLOGICAL STUDIES ON INTERSEX
REORT2: OBSERVATIONS ON URINARY STEROIDS IN CASES OF CONGENITAL ADRENOCORTICAL HYPERPLASIA
1965 Volume 56 Issue 2 Pages 198-215
Details
1965 Volume 56 Issue 2 Pages 198-215
Urinary excretion of 17-OHCS, 17-KS, 17α-hydroxypregnanolone, pregnanetriol, estrogen and pregnanediol was determined chromatographically using partially esterified Amberlite IRC-50 in 7 cases of congenital adrenal hyperplasia. In a sixteen-year-old girl, exhibiting 11β-hydroxylation disturbance, were proved high output of THS (41mg/day) and also a slight amout of allo-THS (250μg/day). As to the isomers of pregnanetriol, 5β-pregnane-3α, 17α, 20α-triol, 5α-pregnane-3α, 17α, 20α-triol and 5β-pregnane-3α, 17α, 20β-triol were separated, but their 5β/5α ratios were not in proportionate to those of 11-deoxy-17-oxosteroids
