STUDIES OF RESPIRATION AND GLYCOLYSIS OF VESICLE TUMOR
1965 Volume 56 Issue 7 Pages 686-695
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1965 Volume 56 Issue 7 Pages 686-695
The respiration and glycolysis of vesicle tumors were calculated, comparing with histological findings, of 42 cases out of 68 who has visited the clinic of urology, school of medicine, Chiba Univ. from September 1961 to February 1964.
According to the classification of Dean et al. (1954), the author dicided the tumors into three types; papillom I (beningnancy), papillom II (Suspected malignancy) and carcinoma (undoubted malignancy).
The result of measurement is as follows: Warburg quotient (the ratio of aerobic glycolysis and repiration) indicated remarkable difference between papillom I and malignant tumor, while papilloma II did not necessarily reflect histological findings, showing considerable variation of values according to the portion measured.
Some tumors in papilloma II with marked intraepithelial and multiple growth revealed high anerobic glycolysis and active respiration.
Highly proliferating multiple papillomatons cancer showed also high anerobic and aerobic glycolysis.
Prolongation of measuring time brought about wider difference of Warburg quotient between benign malignant tumors.
In other words, the value indicated, in malignant tumors, less decrease in the course of time.
