GAS CHROMATOGRAPHICAL ANALYSIS ON FATTY ACIDS IN THE PYURIA
1966 Volume 57 Issue 6 Pages 614-618
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1966 Volume 57 Issue 6 Pages 614-618
On fatty acids, many reports have been issued on gas chromatographical studies in the blood, and some paper chromatographical and no gas chromatographical in the urine. This paper describes the gas chromatography of urinary fatty acids in 30 cases of urosis with pyruia, and 5 normal subjects for control values. The results are summarizd as follows:
1) It was found that the majority of the samples contained both the free and esterified fatty acids while others contained only the free or esterified. Neither type of fatty acid could be found from two subjects who had had nephrectomy for unilateral nephrophthisis.
2) The free fatty acids were detected in 25 of 30 samples and the esterified were in 18 of 30.
3) Results from the 30 patients showed that lauric and palmitic acid wer the most frequently occuring free fatty acids while palmitic and myristic were the most important esterified fatty acids.
4) Results of individual subjects showed that palmitic acid was present in the greatest quantity in the free fatty acid while palmitic and stearic were the most abundant esterified fatty acids. This information was made by peak area comparisons on the gas chromatograms.
5) There was no correlation between quality and quantity of fatty acids in pyuria, and the type of disease or microbe associated with that disease.
6) In normal urine, only free fatty acids are found. Palmitic and palmitoleic acid are the most abundant fatty acids in normal urine.
