The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
A STUDY ON SO-CALLED PROSTATITIC EOSINOPHILIA
REPORT X. THE CHARCOT-LEYDEN CRYSTAL FORMING CAPACITY OF MARROW EOSINOPHILS AND THEIR CYTOCHEMICAL ANALYSIS
Susumu Fukuchi
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1968 Volume 59 Issue 10 Pages 910-921

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Abstract

In 35 male cases of Urosis, marrow eosinophils were tested for their Charcot-Leyden crystal forming capacity and their cytochemical analysis.
Results
(1) Eosinophilia was noted in the peripheral blood of 10 out of the 35 cases.
(2) Ten cases of peripheral eosinophilia comprised 3 cases of “prostatitic eosinophilia” (PE).
(3) The 3 cases of “prostatitic eosinophilia” showed a Charcot-Leyden forming capacity in peripheral eosinophils.
(4) Among the 35 cases the massage of the prostate produced a marked increase in marrow eosinophilia in 4 cases, 3 of which showed positive reactions to “PE”.
(5) For the 35 cases the marrow eosinophil counts ranged from 81 to 875.
(6) Cytochemical findings in the marrow eosinophils of 3 cases of “PE” were the positive reactions of the silver test, millon's test, the azo test and the chromatin test, whereas normal findings were noted in the remaining 32 cases.
(7) The marrow of 3 cases of “PE” was as normal as in the 32 cases, except that the eosinophil count was great.
(8) Following the massage of the prostate in 3 cases of “PE”, marrow eosinophils increased over 50%, as compared with those before the massage.
(9) After developing into promyelocyes, marrow eosinophils from 3 cases of “PE” were specific eosinophil count increased over 50% due to the massage of the prostate. The Charcot- Leyden crystal forming capacity was also present.
(10) The author wishes to agree with Yamamoto et al. who have interpreted the “PE” phenomenon as a reactive phenomenon due to pathological changes in the allergy of the prostate, including infection or induced allergy through candida, trichomonas, parasites and the like.

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