1969 年 60 巻 12 号 p. 1158-1173
The sensitivity of the eccrine sweat gland to adrenaline and noradrenaline was examined in 70 patients with adrenal, renal and essential hypertension according to the Wada-Takagaki's method. The results were summarized as follows:
1) In aldosteronism, the sensitivity varied over a very wide range. These abnormally elevated or suppressed sensitivities of the eccrine sweat gland approached the normal range after the extirpation of the adrenal tumor or the subtotal adrenalectomy.
2) In Cushing's syndrome, the sensitivity was in normal range or slightly elevated. The postoperative data on the sensitivity also approached the normal range.
3) Patients with pheochromocytoma showed remarkably low sensitivity in the majority of the cases. The sensitivity rapidly elevated after the extirpation of the tumor.
4) The sensitivity of the eccrine sweat gland in renal hypertension was in normal range or slightly elevated.
5) The sensitivity in essential hypertension varied over a wide range.
6) It is probable that these changes in the catecholamine sensitivity of the eccrine sweat gland represtent a part of phenomena of the general change in the catecholamine sensitivity of the whole body.