1969 Volume 60 Issue 4 Pages 321-330
Concerning the relationship between gonadal function and vitamins, reports by various investigators are already available. All of these deal with gonadal function in vitamin deficiency. We have therefore caused a disturbance of spermatogenic function through X-ray irradiation experimentally using adult rats of Wistar strain to study the influence of V-B1, V-E, V-B12, V-B1, B6, B12 complex, and pantethine on their recovery process. In order to study the relationship between the testicular storma and vitamins, these vitamins were administered following cadmium chloride administration to see the effect of these vitamins on the recovery process of the stroma. Administration of these vitamins facilitated the spermatogenetic function but administration of vitamin E and vitamin B12 alone in a large dose rather inhibit the spermatogenetic function. Upon administration as the complex, even at a dose producing disturbance in administration of a single substance, stimulation of the spermatogenetic function was rather found to our interest. The effect of vitamins was not so pronounced against a disturbance of spermatogenetic function such as X-ray injury. As compared with the group treated by X-ray irradiation alone, the revovery of spermatogenetic function was more pronounced. In the metabolic aspect, changes in the metabolic pattern corresponding to various vitamins might indicate the effect of vitamins in the metabolic aspect. The changes in the stroma might also indicate the facilitation of recovery due to vitamin administration.
