泌尿器科領域, 特に尿路結石症患者における骨鉱物質量のX線学的測定

抄録

In recent years, studies of the quantitative analysis on the mineral contents of the bone by means of densitometry of the roentgenogram of the forearm have been made in fields of medicine. In the urological field, however, this investigation is still scanty though its clinical application may lead to worthy information as to the diagnosis and treatment of the metabolic imbalance of calcium or phosphor.
The authors determined the mineral contents of the ulna in 28 patients with urolithiasis and 35 healthy adults by X-rays.
The patient's right forearm was placed in a water-phantom containing a wetting agent in order to standardize the thickness of the non-osserous tissues. The points 3.6cm above the distal edge of the ulna to be examined were chosen. The quantity of the bone salt in the above-mentioned portion was compared with an aluminium step wedge (7 steps of 2cm width, 0.5mm thick, from 0.5 to 5mm) by the densitometric measurement at the same points on the roentgenogram.
The results obtained in the clinical cases were as follows:
1. The mean value of healthy males was 388±105.8mg/cm³, healthy females was 345±131.2mg/cm³. 2. The mean value of male patients with urolithiasis was 304±81.2mg/cm³, female patients was 242±90.2mg/cm³. 3. There was found to be a tendency of higher mineral contents in the male than in the female. 4. No significant difference of the mineral contents was found between the groups of urolithiasis and healthy adults. 5. A 25-year-old male of suspected hyperparathyroidism with a high urinary hydroxyproline excretion showed a significantly low value (156mg/cm³) of the mineral contents. The authors emphasized that, the objective or quantitative evaluation of the roentgenogram should play a more important role in X-ray diagnosis in the future.