日本泌尿器科學會雑誌
Online ISSN : 1884-7110
Print ISSN : 0021-5287
血液透析に関する研究
第2報 病理組織学的検討
三橋 慎一瀬川 襄梶本 伸一村上 信乃真鍋 薄百瀬 剛一井出 源四郎長尾 孝一松嵜 理
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1973 年 64 巻 3 号 p. 217-230

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1) Six autopsy cases previously treated by hemodialysis from 1967 to 1970 at the Urological Department of School of Medicine Chiba University are presented and the autopsy findings are specially described.
2) The superficial findings of the kidneys of patients with long term hemodialysis appeared to be smooth. Histopathologically there were no compensatory changes and marked oxal crystal deposit in the lumen of the tubules.
3) Deposition of eosinophilic substance was visible in the walls of the intrarenal small arteries, glomerular capillaries and tubules. There was a considerable thickening of basement membrane of the tubules. Hemoglobin was present within the tubule and rhomboid crystal appeared in the lumen of some small arteries.
4) All the cases had pericarditis to various extent. Some of the patients died of this disease.
5) On chronic hemodialysis, parathyroid glands of the patients were atrophic, while clear cells were rather preserved.
6) There was resorption of bone and osteoporosis was markedly significant.

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