1976 Volume 67 Issue 5 Pages 321-325
For 51 cases with carcinoma of the prostate, the interrelationship between clinical effect by anti-androgenic treatment with castration and stilbestrols and change of serum lactic dehydrogenase and its isoenzyme V levels were studied and the following results were obtained.
1. Pretreatment serum lactic dehydrogenase level had significant correlation with five-year survival rate.
2. Response of serum lactic dehydrogenase and its isoenzyme V levels to antiandrogenic treatment has no significant meaning on five-year survival rates.
3. As an index of treatment in patients with prostatic carcinoma, serum lactic dehydrogenase isoenzyme V was not specific more than serum lactic dehydrogenase.