MULTIPLE PRIMARY MALIGNANT NEOPLASMS ASSOCIATED WITH GENITO-URINARY ORGANS
REPORT OF TWELVE CASES AND REVIEW OF THE LITERATURE
1980 Volume 71 Issue 6 Pages 597-606
Details
1980 Volume 71 Issue 6 Pages 597-606
During the past 10-year period, a total of twelve patients had been diagnosed as multiple primary malignant neoplasm at our clinic. These patients were composed of eleven male and one female patient. The ages of these patients at diagnosis of the second neoplasm ranged from 60 to 81 years, with a mean of 7203 years. Three patients had lesions that were diagnosed simultaneously; nine patients metachronously. The average interval between the first and second neoplasms was 10 years and 1 month.
The combinations of sites were often seen in the gastro-intestinal tract: in 3 cases in the stomach and in 4 in the colo-rectal area. Two rare combinations of immunoblastic lymphadenopathy were observed in patients with bladder cancer, and gastric reticulum cell sarcoma in one with prostatic cancer. No family history of malignancy was noted in these patients.
Three hundred and twenty-five cases of primary malignant neoplasms collected from the recent Japanese literature were reviewed and discussed.
