1984 Volume 75 Issue 5 Pages 802-806
Serum prostate antigen (PA) levels in 158 apparently healthy Japanese were detected with an enzyme immunoassay and these values were compared with those of Americans (n=68). Of 26 sera from females, 2 cases have serum PA of 0.12 and 0.13ng/ml, respectively. However, in others (92%) serum PA was undetectable (<0.10ng/ml). A total of 132 sera from males (age; 17-57 y. o., average; 30.7) were evaluated for serum PA values. Of these, in 42 sera (32%), PA could not be detected. Regrading these sera having 0.10ng/ml of PA, the mean±SD was 0.33±0.28ng/ml. One point two ng/ml, mean+3S. D., was calculated as an upper cut-off value in normal Japanese males. In prostate cancer patients with pretreatment (n=45), 28 cases (62%) were shifted to positive from 23 patients (51%) whose serum PA levels were greater than an upper cut-off value in Americans, which is 2.5ng/ml.
