1985 Volume 76 Issue 6 Pages 850-858
Superficial bladder tumors of the stages of T2 or below pT2 were studied in 161 patients admitted and treated in our Department with special reference to the recurrence rate. The recurrence rate was determined by the actuarial method and tested by χ2 test.
1. Superficial bladder tumors as a whole tended to show a markedly high recurrence rate in 0.5-1.5 years.
2. When compared between the papillary and non-papillary tumors and between the mono-and multi-tumors, no significant differences were noted in the recurrence rate.
3. When analyzed from the histological stage, pT1 showed a significantly higher recurrence rate in 2-4 years compared to pTis. However, no significant differences were found in other stages.
4. When analyzed from the histological grade, a significantly higher recurrence rate was demonstrated by G3 in 1-1.5 years compared to G0, G1 and G2, and by G2 in 3-4 years compared to G0.
5. When viewed from the opeartive technique, there were no significant differences in the recurrence rate as to the type of surgical techniques. Oral administration of SLA combined with intravesicular instillation of antitumor agents had an effect of prolonging the non-recurrence duration.
6. Early postoperative intravesicular instillation of anti-tumor agents to be continued by long-term intermittent instillation is considered desirable for the control of tumor recurrence.