STAGE A CARCINOMA OF THE PROSTATE: HISTOLOGY IN RELATION TO SURVIVAL RATE

Abstract

We reviewed 60 cases of incidental carcinoma treated conservatively. Five year survival rate depending histological grade of Mostofi's, differentiation and Gleason's classification showed a significant difference. Cases in which well differentiated adenocarcinoma involved≤3 chips in a transzrethrally resected specimen or ≤5mm diameter of total lesion in an enucleated specimen were classifieu as stage A₁ (30 cases) and all others were classified as stage A₂ (30 cases). Patients with stage A₁ tumors significantly were better (P less than 0.05) than those with A₂, the 5 year survival rates being 88% and 69%, respectively. We believe that patients in stage A₂ should be treated aggressively. However, we recommend conservative therapy for patients in stage A₁.