STUDIES ON RENAL DAMAGE IN PERCUTANEOUS NEPHROURETEROLITHOTOMY
A MORPHOLOGICAL STUDY
1988 Volume 79 Issue 1 Pages 150-154
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1988 Volume 79 Issue 1 Pages 150-154
We studied the effects of nephrostomy performed as part of percutaneous nephroureterolithotomy in the kidneys of adult mongrel dogs.
The influences of the duration of the fistula on changes in the tissue was evaluated. However, no difference was found in the tissue among different duration groups; atrophy in the glomeruli and compression, dilation, and degeneration in the renal tubules were commonly observed only in the area adjacent to the fistulous tract. Only the group in which the tract was left unclosed for a long period showed split formation and surface epithelialization in the medullary area of the tract.
Tissue regeneration after closure of the tract occurred earlier in the cortex than in the medulla. Intraparenchymal infiltration of blood cells remained 3days later, but a linear scar was formed 21days later.
In addition, vascular changes were evaluated by soft ray examination after infusing micropague with colored gelatin via the renal artery. Peripheral blood vessels could be visualized clearly, and no vascular changes caused by nephrostomy were observed.
