1988 Volume 79 Issue 3 Pages 539-546
Human external urethral sphincter (EUS) muslce was isolated from urethrae obtained in surgery by glycerination. Electrophoretic samples were made from the isolated EUS muscle and pyrophosphate electrophoresis and two-dimensional electrophoresis were performed. Denatured myosin isozymes and myosin light chain components from EUS muscle were analysed by pyrophospahte electrophoresis and two-dimensional electrophoresis, respectively. Human EUS was concluded to be comprised with both fast twitch and slow twitch muscle fibers. The distribution of fast and slow myosin in EUS was examined in six cases. The distribution was various from case to case. In no case the percentage of slow twitch myosin was less than 38.8%.