The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
BIOCHEMICAL ANALYSIS OF HUMAN EXTERNAL URETHRAL SPHINCTER
Sohei TokunakaHiromitsu FujiiKiyoharu OkamuraMasanobu MiyataShigeo KanekoSunao Yachiku
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1988 Volume 79 Issue 3 Pages 539-546

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Abstract

Human external urethral sphincter (EUS) muslce was isolated from urethrae obtained in surgery by glycerination. Electrophoretic samples were made from the isolated EUS muscle and pyrophosphate electrophoresis and two-dimensional electrophoresis were performed. Denatured myosin isozymes and myosin light chain components from EUS muscle were analysed by pyrophospahte electrophoresis and two-dimensional electrophoresis, respectively. Human EUS was concluded to be comprised with both fast twitch and slow twitch muscle fibers. The distribution of fast and slow myosin in EUS was examined in six cases. The distribution was various from case to case. In no case the percentage of slow twitch myosin was less than 38.8%.

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© Japanese Urological Association
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