1988 Volume 79 Issue 3 Pages 547-551
4-hour fasting urine collection from 7AM to 11AM was tried in 117 patients with idiopathic urinary Ca stone disease and comparisons of urinary calcium (Ca), phosphorus (P), magnesium (Mg) and uric acid (U. A) excretions were made between 4-hour fasting urine collection and standard 24 hour urine collection.
The results were as follows:
1) Urinary excretions of Ca, P, Mg, (mg/g, creat) in 4-hour urine collection were lower than those in 24hour urine collection with significant difference (P<0.01) probably due to effect of fasting, while there was positive correlation in urinary Ca, P, Mg excretions between these two urine collections (p<0.01). In U. A. urinary excretions, there was no significant difference between two urine collections, but posivite correlation was recognized (p<0.01).
2) 13 patients with idopathic hypercalciuria in urinary stone patients were classified according to Pak's method into 2 groups, 9 patients with absorptive hypercalciuria (A. H.) and 4 patients with renal hypercalciuria (R. H.). Ca excretions in 4-hour urine collection (mg/4hrs) were compared between these two groups. Ca excretions in patients with R. H. were significantly higher than those in patients with A. H. (p<0.05).
From these results, it was suggested that 4hour fasting urine collection would be useful for differential diagnosis of idiopathic hypercalciuria.
