A CASE REPORT OF RENOVASCULAR HYPERTENSION DUE TO RENAL ARTERY BRANCH OBSTRUCTION

Determination of Segmental Renal Venous Renin Activity and Intra Renal Tissure Renin Concentration

Abstract

We report a case of renovascular hypertension due to renal artery branch obstruction. Preoperatively, selective segmental renal vein catheterization was used to obtain venous blood sample for renin assay. By this technique a localized source of hyperreninemia was identified as left upper and middle segmental area. After left nephrectomy, the renal tissure renin concentration of ischemic area was remarkably elevated. Also the hypertropy of JG cells was observed by histological examination.
These results show that the hyperreninemia is due to high renin production from the ischemic part of the kidney.