Abstract
Dynamics of the glycogen content changes in the reference to the histopathological changes of the liver in the course of experimental babesiosis in mice was studied on days: 7, 14 and 28 post infection. On days 7 and 14 post infection an increase in the Kupffer cell activity, lymphocyte infiltrations, liquefactive necrosis, and liver hyperemia were recorded. On day 14 post infection hemorrhagic ecchymoses – resulting from endothelial damage (mainly sinusoidal vessels) and causing fragmentation of the parenchyma - were observed. Those changes were intensified on day 28 post infection. From day 14 post infection on, a continuous decrease of glycogen content was observed. The weakest PAS reaction occurred in the mouse liver on day 28 post infection.
