The Journal of Protozoology Research
Online ISSN : 2434-7027
Print ISSN : 0917-4427
Studies of Liver of Mice in the Course of an Experimental Infection with Babesia microti. I: Histopathological Changes and Changes in the Glycogen Content
WANDA KUZNA-GRYGIELLIDIA KOLODZIEJCZYK
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2000 年 10 巻 1 号 p. 14-23

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Dynamics of the glycogen content changes in the reference to the histopathological changes of the liver in the course of experimental babesiosis in mice was studied on days: 7, 14 and 28 post infection. On days 7 and 14 post infection an increase in the Kupffer cell activity, lymphocyte infiltrations, liquefactive necrosis, and liver hyperemia were recorded. On day 14 post infection hemorrhagic ecchymoses – resulting from endothelial damage (mainly sinusoidal vessels) and causing fragmentation of the parenchyma - were observed. Those changes were intensified on day 28 post infection. From day 14 post infection on, a continuous decrease of glycogen content was observed. The weakest PAS reaction occurred in the mouse liver on day 28 post infection.
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© 2000 National Research Center for Protozoan Diseases, National University Corporation Obihiro University of Agriculture and Veterinary Medicine
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